Table 3. Multivariate analysis of factors associated with OS and MFS.
| Hazard ratio | 95% CI | P value | |
|---|---|---|---|
| OS | |||
| FAK expression | |||
| FAK+/pFAK+ versus FAK−/pFAK− | 4.947 | 2.843–8.606 | <0.001 |
| FAK+/pFAK− versus FAK−/pFAK− | 2.072 | 1.141–3.761 | 0.017 |
| Histological response to pre-operative chemotherapy | |||
| poor versus good | 2.047 | 1.294–3.237 | 0.024 |
| MFS | |||
| FAK expression | |||
| FAK+/pFAK+ versus FAK−/pFAK− | 4.915 | 2.907–8.311 | <0.001 |
| FAK+/pFAK− versus FAK−/pFAK− | 1.785 | 0.992–3.213 | 0.053 |
| Histological response to pre-operative chemotherapy | |||
| poor versus good | 2.058 | 1.321–3.205 | 0.001 |
Variables were adopted for their prognostic significance by univariate analysis with enter-stepwise selection (P < 0.05).
Abbreviations: CI, confidence interval; OS, overall survival; MFS, metastasis-free survival; FAK, focal adhesion kinase