Table 1. Clinical factors and NKD1 methylation in 196 cases of gastric cancer samples.
| Clinical factor | No. | NKD1 methylation status | P*value | |
|---|---|---|---|---|
| Methylated n = 23 (11.7%) | Unmethylated n = 173 (87.2%) | |||
| Age (year) | ||||
| <50 | 40 | 3 | 37 | P = 0.5109 |
| ≥50 | 156 | 20 | 136 | |
| Gender | ||||
| Male | 138 | 16 | 122 | P = 0.9249 |
| Female | 58 | 7 | 51 | |
| Tumor Size (cm) | ||||
| ≤5 | 110 | 13 | 97 | P = 0.9672 |
| >5 | 86 | 10 | 76 | |
| Tumor Location | ||||
| Upper | 42 | 3 | 39 | P = 0.3624 |
| Middle | 55 | 9 | 46 | |
| Lower | 99 | 11 | 88 | |
| Differentiation | ||||
| Well | 10 | 0 | 10 | P = 0.1596 |
| Moderate | 57 | 4 | 53 | |
| Poor | 129 | 19 | 110 | |
| TNM Stage | ||||
| I | 17 | 1 | 16 | P = 0.5921 |
| II | 51 | 8 | 43 | |
| III | 101 | 10 | 91 | |
| IV | 27 | 4 | 23 | |
| Distant metastasis | ||||
| M0 | 174 | 20 | 154 | P = 0.9542 |
| M1 | 22 | 3 | 19 | |
| Vessel Invasion | ||||
| Negative | 115 | 14 | 101 | P = 0.9982 |
| Positive | 81 | 9 | 72 | |
*
P values are obtained from chi-square test, significant difference, P < 0.05