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. 2015 Oct 15;6(37):40036–40052. doi: 10.18632/oncotarget.5486

Table 4. Substrate specificity of some SLC16 family members.

Gene (Alt. name) Kmpyruvate (mM) Kmlactate (mM) Km2-hydroxybutyrate (mM) Kmacetoacetate (mM)
SLC16A1 (MCT1) 0.7 4.5 2.6 5.5
SLC16A7 (MCT2) 0.08 0.74 ND 0.8
SLC16A8 (MCT3) ND 6 ND ND
SLC16A3 (MCT4) 153 28 56 216

Km values for pyruvate, L-lactate, D,L-2-hydroxybutyrate and acetoacetate are given from [19]. ND – no detectable transport was observed.