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. 2015 Oct 14;6(35):37737–37749. doi: 10.18632/oncotarget.5648

Figure 7. CCL5 is necessary and sufficient for increased LLC cell invasion.

Figure 7

A. The invasion properties of LLC cells were assessed by the Boyden chamber assay in the presence of JDP2 −/− BMDC CM supplemented with a mixture of purified CCL3, 4 and 5 (10 ng/ml and 100 ng/ml). C. CM from wild type or JDP2 −/− BMDCs in the presence of anti-CCL5 neutralizing antibodies or anti-cFos antibodies (as control) or E. CCL5 (100 ng/ml) added to the BMDC CM of either wild type or JDP2 −/− mice. The percentage of cell coverage per field was quantified (n > 8 fields/group) (B, D and F, respectively). *, p < 0.05; ***, p < 0.001 using one way ANOVA followed by a Tukey post-hoc test.