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. 2015 Oct 13;6(35):38296–38307. doi: 10.18632/oncotarget.5699

Table 1. Patient Demographics and Clinical Characteristics.

Number of patients (tertile of SUVmax-T, SUVmax-N and EBV DNA, n = 874)
Characteristic SUVmax-T P SUVmax-N P EBV DNA, copies/mL P
<10.7 10.7–16.1 ≥16.1 <5.7 5.7–12.3 ≥12.3 <629 629–9,820 ≥9,820
Age, years
Median 48 46 48 46 48 47 46 47 48
Sex 0.527 0.380 0.894
 Female 63 72 61 61 74 61 64 64 68
 Male 229 220 229 232 220 226 227 228 223
Histology, WHO type 0.873 0.019 0.318
 II 8 7 9 2 13 9 5 11 8
 III 284 285 281 291 281 278 286 281 283
Clinical stage 0.242 <0.001 <0.001
 III 196 178 179 225 179 149 235 190 128
 IVa-b 96 114 111 68 115 138 56 102 163
Tumor stage <0.001 0.009 <0.001
 T1 19 6 5 8 8 14 13 6 11
 T2 55 29 5 20 39 30 20 33 36
 T3 167 177 189 203 169 161 214 177 142
 T4 51 80 91 62 78 82 44 76 102
Node stage 0.192 <0.001 <0.001
 N0 34 41 33 94 11 3 60 33 15
 N1 84 96 113 124 102 67 134 103 56
 N2 124 112 107 65 133 145 83 127 133
 N3 50 43 37 10 48 72 14 29 87
Treatment 0.512 <0.001 <0.001
 RT 17 23 16 26 16 14 27 18 11
 CCRT 103 84 93 125 84 71 133 93 54
 NACT+CCRT 164 180 176 133 190 197 130 171 219
 CCRT+AC 8 5 5 9 4 5 1 10 7
Radiotherapy technique 0.525 0.823 0.168
 2DRT/3DCRT 73 70 81 72 75 77 70 68 86
 IMRT 219 222 209 221 219 210 221 224 205
VCA-IgA 0.210 0.020 <0.001
 <1:80 84 89 70 99 73 71 108 82 53
 ≥1:80 208 203 220 194 221 216 183 210 238
EA-IgA 0.156 <0.001 <0.001
 <1:10 126 129 107 150 102 110 153 119 90
 ≥1:10 166 163 183 143 192 177 138 173 201
Smoking 0.302 0.132 0.09
 No 170 188 180 191 183 164 194 172 172
 Yes 122 104 110 102 111 123 97 120 119
Family history of NPC 0.855 0.876 0.102
 No 258 262 257 261 263 253 266 261 250
 Yes 34 30 33 32 31 34 25 31 41

Abbreviations: 2DRT = two-dimensional radiotherapy; 3DCRT = three-dimensional conformal radiotherapy; IMRT = intensity-modulated radiotherapy; VCA = viral capsid antigen; EA = early antigen; NPC = nasopharyngeal carcinoma follow-up; RT = radiation alone; CCRT = concurrent chemoradiotherapy; NACT + CCRT = neoadjuvant chemotherapy + concurrent chemoradiotherapy; CCRT + AC =concurrent chemoradiotherapy + adjuvant chemotherapy