Table 1.

ECS volume fraction (α), tortuosity (λ), and TMA⁺ loss parameter (k′) in the somatosensory neocortex of AQP4^+/+ and AQP4^−/− mice before, during and after CSD.

	before CSD	during CSD	30 min after CSD
AQP4+/+
α	0.18 ± 0.003	0.045 ± 0.005	0.19 ± 0.004
λ	1.61 ± 0.02	2.27 ± 0.15	1.64 ± 0.04
k′	0.0031 ± 0.0009	0.038 ± 0.005	0.0055 ± 0.0007
n	6	4	4
AQP4−/−
α	0.23 ± 0.007**	0.055 ± 0.003	0.24 ± 0.005
λ	1.62 ± 0.04	2.38 ± 0.21	1.68 ± 0.03
k′	0.0045 ± 0.0001	0.02718 ± 0.006	0.0038 ± 0.0002
n	6	4	4

Data are expressed as mean ± SEM with n mice per group.

^**P < 0.001 (two- sample equal variance t-test) comparing AQP4^+/+ and AQP4^−/− mice.