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. Author manuscript; available in PMC: 2017 Jan 15.
Published in final edited form as: Virology. 2015 Nov 21;488:88–95. doi: 10.1016/j.virol.2015.11.005

Figure 5. SEVI does not increase viral load or the rate of mucosal transmission of HIV-1 in TKO-BLT mice.

Figure 5

Levels of p24 in plasma of infected humanized mice were determined at 2 weeks after the first infection (A) and 4 weeks after the second infection (B) by p24 ELISA as described in Figure 3 and the methods section. The dotted line denotes the limit of detection (3.125 pg/mL). Contingency table analysis by Fisher’s exact test showed no difference between the two groups at either 2wpi (P= 1.0000) or 4wpi (P= 0.5692). The mean levels of human CD45+ cells in the blood before infections exceeded 5 x 105/ml blood for both groups and mean CD4+ T cell levels exceeded 2 x 105/ml blood (data not shown).