Table 1. Clinical features of EAE in mice in the administration of vehicle, tIL12rβ1/Fc or CsA.
Group | Treatment regimen | Preventive regimen | ||
---|---|---|---|---|
Incidence, % | Mean maximal score | Incidence, % | Mean maximal score | |
Vehicle | 100 | 3.25 ± 0.35 | 100 | 2.95 ± 0.44 |
tIL12rβ1/Fc | 100 | 1.90 ± 0.46*** | 70 | 1.10 ± 0.62*** |
CsA | 100 | 2.30 ± 0.43*** | 80 | 1.20 ± 0.75*** |
Values are expressed as mean ± SD
p < 0.001 compared with vehicle control.