Figure 1. A. and B.

Real-Time PCR for TNF-α. The gene expression levels of TNF-α had a similar trend in co-culture and co-culture with silenced YKL-40: TNF-α mRNA increased significantly in HFs, reaching the highest level at 72 h and 96 h, whereas in the tumor cells, it remained constant and low. * represents a significant difference from HF cells grown in normal co-culture, P < 0.05. # represents a significant difference from MG-63 cells grown in normal co-culture, P < 0.05.