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. 2016 Feb 3;2016:bcr2015214225. doi: 10.1136/bcr-2015-214225

Making a dent with corticosteroid injections for de Quervain's tenosynovitis

Andre Khoo 1, Clive E Grattan 1
PMCID: PMC4746548  PMID: 26843225

Description

A 71-year-old patient presented with an abnormal patch of skin on the radial aspect of her right wrist (figures 1and 2). Eighteen months previously, she had undergone an intra-tendon sheath steroid injection (0.25 mL triamcinolone 40 mg/mL) at the site, for de Quervain's tenosynovitis. In the weeks following the injection, she noticed marked indentation of the skin surrounding the injection point, followed by tenderness and a predisposition to bruising. Examination revealed an atrophic patch of skin with a central ecchymosis from mild accidental trauma. These findings would be consistent with a lipo-atrophy and dermal-atrophy.

Figure 1.

Figure 1

Medial view of atrophic skin on right wrist centred on injection point. A prominent vein is visible in the middle of this area.

Figure 2.

Figure 2

View of lesional skin from the anterior of the wrist demonstrating the marked indentation of the atrophic skin.

Skin atrophy is a well-known complication of topical and systemic steroid treatment. However, atrophy from intratendon sheath injections is much less common, and may arise from leakage of the steroid preparation into the subcutaneous tissues. A related phenomenon is linear atrophy and hypopigmentation resulting from the lymphogenous spread of the steroid.1

Treatment options are limited. We discussed simple observation or excision of the affected area and emplacement of a full-thickness skin graft. Intradermal fillers with saline or autologous fat transplants have also been tried.2 3

Learning points.

  • Skin atrophy is a potential complication of intratendon sheath steroid injections and patients should be warned of this as part of their consent process.

  • Skin atrophy from intratendon sheath steroid preparations can be rapid due to the potency and persistence of the steroid in the subcutaneous tissues.

  • Steroid skin atrophy is irreversible if the dermis is involved, and treatment options include observation, excision with grafting and intradermal fillers.

Footnotes

Contributors: AK was involved in the management of the patient, and prepared the article and submitted it for publication. CEG was the overseeing consultant for the patient, was also involved in the direct management of the patient, and reviewed the manuscript prior to submission.

Competing interests: None declared.

Patient consent: Obtained.

Provenance and peer review: Not commissioned; externally peer reviewed.

References

  • 1.Friedman SJ, Butler DF, Pittelkow MR. Perilesional linear atrophy and hypopigmentation after intralesional corticosteroid therapy. Report of two cases and review of the literature. J Am Acad Dermatol 1988;19:537–41. 10.1016/S0190-9622(88)70209-1 [DOI] [PubMed] [Google Scholar]
  • 2.Latoni JD, Marshall DM, Wolfe SA. Overgrowth of fat autotransplanted for correction of localized steroid-induced atrophy. Plast Reconstr Surg 2000;106:1566–9. 10.1097/00006534-200012000-00018 [DOI] [PubMed] [Google Scholar]
  • 3.Shumaker PR, Rao J, Goldman MP. Treatment of local, persistent cutaneous atrophy following corticosteroid injection with normal saline infiltration. Dermatol Surg 2005;31:1340–3. 10.1097/00042728-200510000-00016 [DOI] [PubMed] [Google Scholar]

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