Table 2. Effect of cetuximab on fluidity of membrane in ABCB1 transporter overexpressing cells.

	Flourscence Polarization(P)
	KBv200	MCF-7/adr
Control	0.285 ± 0.007	0.229 ± 0.003
111.11 μg/ml Cetuximab	0.297 ± 0.010*	0.241 ± 0.005*
166.66 μg/ml Cetuximab	0.302 ± 0.004**	0.246 ± 0.013*
250 μg/ml Cetuximab	0.308 ± 0.008**	0.252 ± 0.003**

A fluidity of tumor cell membrane assay was performed as previously described in “Materials and Methods”. Data represent Mean ± SD of at least three independent experiments.

^“*”P < 0.05,

^“**”P < 0.01.