Table.
Baseline Clinical and Imaging Parameters in Different Subgroups and Overall Study Population
| All Patients MCA | Superficial MCA (n=279) | Deep MCA (n=128) | Both (n=88) | Group Comparison | |
|---|---|---|---|---|---|
| Age (mean, SD) | 66±15 | 67.1±14.7 | 64.3±15.8 | 65±14.8 | P=0.203 |
| Sex | |||||
| Men | 263 (53%) | 163 (58.4%) | 55 (43%) | 45 (51.1%) | |
| Women | 233 (47%) | 116 (41.6%) | 73 (57%) | 43 (48.9%) | P=0,014 |
| NIHSS (mean, SD) | 10.3±7.1 | 8.7±6.5 | 9.4±6.4 | 16.8±6.6 | P<0.0001 |
| Cause (TOAST) | P=0.679 | ||||
| Large artery atherosclerosis | 139 (28%) | 71 (25.4%) | 41 (32%) | 26 (29.5%) | |
| Cardioembolism | 150 (30.2%) | 95 (34.1%) | 28 (21.9%) | 27 (30.7%) | |
| Small-vessel occlusion | 21 (4.2%) | 4 (1.4%) | 17 (13.3%) | 0 | |
| Stroke of other determined cause | 36 (7.3%) | 14 (5%) | 11 (8.6%) | 11 (12.5%) | |
| Stroke of undetermined cause | 64 (12.9%) | 43 (15.4%) | 14 (10.9%) | 7 (8%) | |
| ASPECTS (median, IQR) | 9, 7–9 | 9, 7–9 | 9, 9–9 | 6, 5–7 | P<0.0001 |
| DWI lesion volume (mean, SD), Ml | 25±38.6 | 21.2±30.8 | 7.2±17.7 | 67.8±54.6 | P<0.0001 |
Group comparison was conducted using the Kruskal–Wallis Test. ASPECTS indicates Alberta Stroke Program Early Computed Tomographic Score; DWI, diffusion-weighted imaging; IQR, interquartile range; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; and TOAST, Trial of Org 10 172 in Acute Stroke Treatment.