The following paper had incorrect IC50 values in Table 1; the values should be the same as given in Table 2:
Table 1 with incorrect values is below.
Table 1.
IC50 values (inhibition in antagonist mode) for human PPARα, PPARδ and PPARγ.
| Human PPAR | NXT629
|
NXT962
|
|---|---|---|
| PPARα | 78 nmol/L | >15,000 nmol/L |
| PPARδ | >30,000 nmol/L | >30,000 nmol/L |
| PPARγ | >30,000 nmol/L | >30,000 nmol/L |
Table 1 with correct values is below.
Table 1.
IC50 values (inhibition in antagonist mode) for human PPARα, PPARδ and PPARγ.
| Human PPAR | NXT629
|
NXT962
|
|---|---|---|
| PPARα | 77 nmol/L | >30,000 nmol/L |
| PPARδ | 6,000 nmol/L | >30,000 nmol/L |
| PPARγ | 15,000 nmol/L | >30,000 nmol/L |
Footnotes
Online address: http://www.molmed.org
