Abstract
A patient with proven Legionnaire's disease is described whose clinical condition improved with intravenous azithromycin after failure to respond to treatment with erythromycin and rifampicin.
Full text
PDF

Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Fitzgeorge R. B., Featherstone A. S., Baskerville A. Efficacy of azithromycin in the treatment of guinea pigs infected with Legionella pneumophila by aerosol. J Antimicrob Chemother. 1990 Jan;25 (Suppl A):101–108. doi: 10.1093/jac/25.suppl_a.101. [DOI] [PubMed] [Google Scholar]
- Foulds G., Shepard R. M., Johnson R. B. The pharmacokinetics of azithromycin in human serum and tissues. J Antimicrob Chemother. 1990 Jan;25 (Suppl A):73–82. doi: 10.1093/jac/25.suppl_a.73. [DOI] [PubMed] [Google Scholar]
- Hoepelman A. I., Sips A. P., van Helmond J. L., van Barneveld P. W., Neve A. J., Zwinkels M., Rozenberg-Arska M., Verhoef J. A single-blind comparison of three-day azithromycin and ten-day co-amoxiclav treatment of acute lower respiratory tract infections. J Antimicrob Chemother. 1993 Jun;31 (Suppl E):147–152. doi: 10.1093/jac/31.suppl_e.147. [DOI] [PubMed] [Google Scholar]
- Mercatello A., Frappaz D., Robert D., Bornstein N., Fleurette F. Failure of erythromycin/rifampicin treatment of legionella pneumonia. J Infect. 1985 May;10(3):282–283. doi: 10.1016/s0163-4453(85)92838-5. [DOI] [PubMed] [Google Scholar]
- Moffie B. G., Mouton R. P. Sensitivity and resistance of Legionella pneumophila to some antibiotics and combinations of antibiotics. J Antimicrob Chemother. 1988 Oct;22(4):457–462. doi: 10.1093/jac/22.4.457. [DOI] [PubMed] [Google Scholar]
- Retsema J., Girard A., Schelkly W., Manousos M., Anderson M., Bright G., Borovoy R., Brennan L., Mason R. Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms. Antimicrob Agents Chemother. 1987 Dec;31(12):1939–1947. doi: 10.1128/aac.31.12.1939. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schönwald S., Gunjaca M., Kolacny-Babić L., Car V., Gosev M. Comparison of azithromycin and erythromycin in the treatment of atypical pneumonias. J Antimicrob Chemother. 1990 Jan;25 (Suppl A):123–126. doi: 10.1093/jac/25.suppl_a.123. [DOI] [PubMed] [Google Scholar]
- Zuravleff J. J., Yu V. L., Shonnard J. W., Davis B. K., Rihs J. D. Diagnosis of Legionnaires' disease. An update of laboratory methods with new emphasis on isolation by culture. JAMA. 1983 Oct 21;250(15):1981–1985. doi: 10.1001/jama.250.15.1981. [DOI] [PubMed] [Google Scholar]


