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. 1994 Aug;49(8):836–837. doi: 10.1136/thx.49.8.836

Congenital cutis laxa with a dominant inheritance and early onset emphysema.

E Corbett 1, H Glaisyer 1, C Chan 1, B Madden 1, A Khaghani 1, M Yacoub 1
PMCID: PMC475135  PMID: 8091333

Abstract

Two cases (mother and daughter) are reported of autosomal dominant cutis laxa which are unusual in being associated with early onset emphysema. Both mother and daughter have been smokers and are heterozygotes for the alpha 1 antitrypsin genotype. The combination of cigarette smoking and subnormal alpha 1 antitrypsin levels may explain the pulmonary spread in these two women who have what is usually a benign form of cutis laxa limited to the skin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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