Abstract
This study describes a simple whole cell agglutination test for tuberculosis in which phenol-killed Mycobacterium tuberculosis H37Ra is used as the antigen. The test gave positive results in 59 of 63 culture-positive cases of tuberculosis due to M. tuberculosis, and in 4 of 11 culture-positive cases due to other mycobacteria. Negative results were recorded in 168 of 171 control subjects. A positive result was one in which a titre of 1/125 or more was recorded.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ALSHABKHOUN A., CHAPMAN P. T., WHITE M. F., DEGROTA A. A study of the double-diffusion gel precipitation test in tuberculous patients with special reference to technical problems. Am Rev Respir Dis. 1960 May;81:704–708. doi: 10.1164/arrd.1960.81.5.704. [DOI] [PubMed] [Google Scholar]
- Affronti L. F., Fife E. H., Grow L. Serodiagnostic test for tuberculosis. Am Rev Respir Dis. 1973 May;107(5):822–825. doi: 10.1164/arrd.1973.107.5.822. [DOI] [PubMed] [Google Scholar]
- Cole R. V., Lazarus A. W., Hedrick H. G. Development and evaluation of a simple latex agglutination test for diagnosis of tuberculosis. Appl Microbiol. 1972 Oct;24(4):525–534. doi: 10.1128/am.24.4.525-534.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Duboczy B. O., White F. C. Further studies with the direct latex agglutination test in tuberculosis. Am Rev Respir Dis. 1969 Sep;100(3):364–371. doi: 10.1164/arrd.1969.100.3.364. [DOI] [PubMed] [Google Scholar]
- Lind A. The gel double diffusion precipitation test in the diagnosis of tuberculosis. Bull Int Union Tuberc. 1964 May;34(1):37–48. [PubMed] [Google Scholar]
- Nassau E., Merrick A. J. The fluorescent antibody test in human tuberculosis: a pilot study. Tubercle. 1970 Dec;51(4):430–436. doi: 10.1016/0041-3879(70)90009-7. [DOI] [PubMed] [Google Scholar]
- Nassau E., Parsons E. R., Johnson G. D. Detection of antibodies to mycobacterium tuberculosis by solid phase radioimmunoassay. J Immunol Methods. 1975 Jan;6(3):261–271. doi: 10.1016/0022-1759(75)90069-1. [DOI] [PubMed] [Google Scholar]
- Nicholls A. C., Pease P. E., Green I. D. Agglutinin response to bacterial infection in acute exacerbations of chronic bronchitis. J Clin Pathol. 1975 Apr;28(4):279–283. doi: 10.1136/jcp.28.4.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PARLETT R. C., YOUMANS G. P. An evaluation of the specificty and sensitivity of a gel double-diffusion test for tuberculosis. Am Rev Respir Dis. 1959 Aug;80:153–166. doi: 10.1164/arrd.1959.80.2.153. [DOI] [PubMed] [Google Scholar]
- Parlett R. C. The present status of the sero-diagnosis of tuberculosis. Bull Int Union Tuberc. 1964 May;34(1):9–35. [PubMed] [Google Scholar]