Table 3. Effect of Cholic Acid and Its Modified Forms on the Properties of the Paclitaxel Loaded Nanocarriers.
diameter
(nm) |
no.
of H-bonds |
|||||
---|---|---|---|---|---|---|
cholic acid (CA) | PTX core | micelle | PTX | CA | PEO | SASA (nm2) |
hydrophobic | 8.1 ± 0.1 | 19.5 ± 4.7 | 0 | 248 | 2783 | 0.3 |
amphiphilic | 8.9 ± 0.2 | 23.8 ± 3.5 | 0 | 466 | 2884 | 2.1 |
hydrophilic | 9.3 ± 0.4 | 24.9 ± 3.3 | 32 | 484 | 2884 | 10.4 |