Abstract
The thyroids of primary thyrotoxicosis patients prepared for partial thyroidectomy with propranolol contained much more lymphoid infiltrate than those prepared with carbimazole. No relation was found between the extent of lymphoid infiltrate in the thyroid and the development of postoperative hypothyroidism either between or within the two drug treatment groups. This study has shown that the extent of thyroid infiltrate should not be used as the major factor in predicting hypothyroidism after subtotal thyroidectomy for primary thyrotoxicosis.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BUCHANAN W. W., KOUTRAS D. A., CROOKS J., ALEXANDER W. D., BRASS W., ANDERSON J. R., GOUDIE R. B., GRAY K. G. The clinical significance of the complement fixation test in thyrotoxicosis. J Endocrinol. 1962 Apr;24:115–125. doi: 10.1677/joe.0.0240115. [DOI] [PubMed] [Google Scholar]
- FULTHORPE A. J., ROITT I. M., DONIACH D., COUCHMAN K. A stable sheep cell preparation for detecing thyroglobulin auto-antibodies and its clinical applications. J Clin Pathol. 1961 Nov;14:654–660. doi: 10.1136/jcp.14.6.654. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GOUDIE R. B., ANDERSON J. R., GRAY K. G. Complement-fixing antithyroid antibodies in hospital patients with asymptomatic thyroid lesions. J Pathol Bacteriol. 1959 Apr;77(2):389–400. doi: 10.1002/path.1700770208. [DOI] [PubMed] [Google Scholar]
- GREENE R. The significance of lymphadenoid changes in the thyroid gland. J Endocrinol. 1950 Nov;7(1):1–6. doi: 10.1677/joe.0.0070001. [DOI] [PubMed] [Google Scholar]
- Hargreaves A. W., Garner A. The significance of lymphocytic infiltration of the thyroid gland in thyrotoxicosis. Br J Surg. 1968 Jul;55(7):543–545. doi: 10.1002/bjs.1800550712. [DOI] [PubMed] [Google Scholar]
- IRVINE W. J., MACGREGOR A. G., STUART A. E. The prognostic significance of thyroid antibodies in the management of thyrotoxicosis. Lancet. 1962 Oct 27;2(7261):843–847. doi: 10.1016/s0140-6736(62)90628-1. [DOI] [PubMed] [Google Scholar]
- Shevach E. M., Jaffe E. S., Green I. Receptors for complement and immunoglobulin on human and animal lymphoid cells. Transplant Rev. 1973;16:3–28. doi: 10.1111/j.1600-065x.1973.tb00115.x. [DOI] [PubMed] [Google Scholar]
- Simpson J. G., Gray E. S., Michie W., Beck J. S. The influence of preoperative drug treatment on the extent of hyperplasia of the thymus in primary thyrotoxicosis. Clin Exp Immunol. 1975 Nov;22(2):249–255. [PMC free article] [PubMed] [Google Scholar]
- Van Welsum M., Feltkamp T. E., De Vries M. J., Doctor R., Van Zijl J., Hennemann G. Hypothyroidism after thyroidectomy for Graves's disease: a search for an explanation. Br Med J. 1974 Dec 28;4(5947):755–756. doi: 10.1136/bmj.4.5947.755. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Volpé R., Farid N. R., Von Westarp C., Row V. V. The pathogenesis of Graves' disease and Hashimoto's thyroiditis. Clin Endocrinol (Oxf) 1974 Jul;3(3):239–261. doi: 10.1111/j.1365-2265.1974.tb01800.x. [DOI] [PubMed] [Google Scholar]
- WHITESELL F. B., Jr, BLACK B. M. A statistical study of the clinical significance of lymphocytic and fibrocytic replacements in the hyperplastic thyroid gland. J Clin Endocrinol Metab. 1949 Nov;9(11):1202-15, illust. doi: 10.1210/jcem-9-11-1202. [DOI] [PubMed] [Google Scholar]
- Young R. J., Beck J. S., Michie W. The predictive value of histometry of thyroid tissue in anticipating hypothyroidism after subtoatl thyroidectomy for primary thyrotoxicosis. J Clin Pathol. 1975 Feb;28(2):94–98. doi: 10.1136/jcp.28.2.94. [DOI] [PMC free article] [PubMed] [Google Scholar]