Skip to main content
NCBI home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1976 May;29(5):458–461. doi: 10.1136/jcp.29.5.458

Serum beta-lipoprotein and other specific protein concentrations in patients with immunocytoma.

G Shulman, S R Lynch, W R Bezwoda, G C Gilich
PMCID: PMC476088  PMID: 180062

Abstract

Serum beta-lipoprotein and other specific protein concentrations were measured in 56 patients suffering from multiple myelomatosis, "benign" paraproteinaemia or Waldenström's macroglobulinaemia and in 56 control subjects. The mean level of B-lipoprotein in untreated patients with multiple myelomatosis and macroglobulinaemia was significantly lower than that of the controls. Patients who responded to chemotherapy showed a rapid return to normal of the beta-lipoprotein concentration, while the level remained unchanged in most of those who did not.

Full text

PDF
458

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADLERSBERG D., SCHAEFER L., DRACHMAN S. R. Development of hypercholesteremia during cortisone and ACTH therapy. J Am Med Assoc. 1950 Nov 11;144(11):909–914. doi: 10.1001/jama.1950.02920110021006. [DOI] [PubMed] [Google Scholar]
  2. Alexanian R., Bergsagel D. E., Migliore P. J., Vaughn W. K., Howe C. D. Melphalan therapy for plasma cell myeloma. Blood. 1968 Jan;31(1):1–10. [PubMed] [Google Scholar]
  3. BARCLAY M., CALATHES D. N., DILORENZO J. C., HELPER A., KAUFMAN R. J. The relation between plasma lipoproteins and breast carcinoma: effect of degree of breast disease on plasma lipoproteins and the possible role of lipid metabolic aberrations. Cancer. 1959 Nov-Dec;12:1163–1170. doi: 10.1002/1097-0142(195911/12)12:6<1163::aid-cncr2820120612>3.0.co;2-2. [DOI] [PubMed] [Google Scholar]
  4. BURSTEIN M., FINE J. M. [On the level of beta-lipoproteins in myelomas and in Waldenstroem's macroglobulinemia]. Rev Hematol. 1959 Oct-Nov;14:380–383. [PubMed] [Google Scholar]
  5. Bernard D. B., Lynch S. R., Bothwell T. H., Bezwoda W. R., Stevens K., Shulman G. Multiple myeloma. II. The value of melphalan. S Afr Med J. 1974 May 18;48(24):1026–1028. [PubMed] [Google Scholar]
  6. Cartwright G. E., Lee G. R. The anaemia of chronic disorders. Br J Haematol. 1971 Aug;21(2):147–152. doi: 10.1111/j.1365-2141.1971.tb03424.x. [DOI] [PubMed] [Google Scholar]
  7. Ghosh P., Evans D. B., Tomlinson S. A., Calne R. Y. Plasma lipids following renal transplantation. Transplantation. 1973 May;15(5):521–523. [PubMed] [Google Scholar]
  8. Hatch F. T. Practical methods for plasma lipoprotein analysis. Adv Lipid Res. 1968;6:1–68. [PubMed] [Google Scholar]
  9. Hobbs J. R. Immunocytoma o' mice an' men. Br Med J. 1971 Apr 10;2(5753):67–72. doi: 10.1136/bmj.2.5753.67. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kellen J. The serum beta-lipoproteins in different human malignant diseases. Neoplasma. 1968;15(2):139–143. [PubMed] [Google Scholar]
  11. Larson P. H. Serum proteins: diagnostic significance of electrophoretic patterns. Hum Pathol. 1974 Nov;5(6):629–640. doi: 10.1016/s0046-8177(74)80035-3. [DOI] [PubMed] [Google Scholar]
  12. Rifkind B. M., Gale M. Hypolipidaemia in anaemia. Implications for the epidemiology of ischaemic heart-disease. Lancet. 1967 Sep 23;2(7517):640–642. doi: 10.1016/s0140-6736(67)90685-x. [DOI] [PubMed] [Google Scholar]
  13. SKANSE B., VON STUDNITZ W., SKOOG N. The effect of corticotrophin and cortisone on serum lipids and lipoproteins. Acta Endocrinol (Copenh) 1959 Jul;31(3):442–450. doi: 10.1530/acta.0.xxxi0442. [DOI] [PubMed] [Google Scholar]
  14. Shulman G. Accuracy and precision in measurement of human serum immunoglobulins G, A and M. S Afr J Med Sci. 1973 Dec;38(3):61–68. [PubMed] [Google Scholar]
  15. Shulman G., Stevens K., Bernard D. B., Bothwell T. H., Bezwoda W. R., Lynch S. R. Multiple myeloma. I. Clinical, biochemical and immunochemical aspects. S Afr Med J. 1974 May 18;48(24):1023–1026. [PubMed] [Google Scholar]
  16. Spikes J. L., Jr, Cohen L., Djordjevich J. The identification of a myeloma serum factor which alters serum beta lipoproteins. Clin Chim Acta. 1968;20(3):413–421. doi: 10.1016/0009-8981(68)90298-2. [DOI] [PubMed] [Google Scholar]
  17. el-Shaboury A. H., Hayes T. M. Hyperlipidaemia in asthmatic patients receiving long-term steroid therapy. Br Med J. 1973 Apr 14;2(5858):85–86. doi: 10.1136/bmj.2.5858.85. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES