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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Hippocampus. 2015 Oct 10;26(3):341–361. doi: 10.1002/hipo.22526

Table 4. Regression parameters corresponding to linear and segmented fits for Ih sensitive electrophysiological properties of CA1 pyramidal neurons along the V–D axis.

Linear regression Segmented regression

Breakpoint Slopes comparison

Cons. Slope Adj. R2 P-value Cons. Slope 1 Slope 2 Adj. R2 P-value Location P-value Diff. P-value
FR at RMP (Hz) 3.14 -0.02 -0.01 0.57 3.5 0.14 -0.09 -0.001 0.39 -1.2 0.39 0.23 0.21
Q (RMP) 2.08 0.002 -0.01 0.73 1.19 -0.012 0.024 -0.005 0.49 0.5 0.7 -0.03 0.23
FR at -65 mV (Hz) 3.06 -0.23 0.22 <0.0001 4.4 0.3 -0.3 0.23* <0.0001 -2.1 0.006 0.6 0.07
Q (-65 mV) 1.2 -0.03 0.15 <0.0001 1.18 -0.05 -0.009 0.155 <0.0001 0.09 0.946 -0.04 0.23
RS (at RMP) -0.21 0.013 0.09 0.0007 -0.1 0.05 0.004 0.12* 0.0003 -1.8 0.017 0.05 0.035
RS at -65mV -0.22 0.028 0.29 <0.0001 -0.2 -0.038 -0.001 0.31* 0.0001 0.54 0.437 0.04 0.029

V–D gradient in Ih sensitive electrophysiological properties of CA1 pyramidal neurons was fitted by linear and segmented regressions. Linear regression had two factors: constant value (Cons.) and slope. Segmented regression had three factors: constant, slope of line one (slope 1) and slope of line two (slope 2). V–D change in a few electrophysiological properties fitted better with segmented regressions than linear regressions

*

significant increase in Adjusted R2;

significant estimation of change point;

significant difference between the slopes of two lines in the segmented regression.