Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1977 Apr;30(4):350–352. doi: 10.1136/jcp.30.4.350

Effect of local exercise and vessel occlusion on fibrinolytic activity.

J A Rennie, B Bennett, D Ogston
PMCID: PMC476409  PMID: 856879

Abstract

Arterial occlusion of the upper limb did not affect the fibrinolytic activity in the venous blood of that limb; venous occlusion associated with venous distension resulted in a marked rise in activity. Local fibrinolytic activity was increased substantially by active exercise; passive exercise induced a smaller increase. Active exercise undertaken during arterial occlusion did not result in a rise in activator level. It is concluded from these results that blood flow into the venous system rather than accumulation of metabolites is responsible for the increased release of activator into the blood during local exercise and vessel occlusion.

Full text

PDF
350

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CLARKE R. L., ORANDI A., CLIFFTON E. E. Induction of fibrinolysis by venous obstruction. Angiology. 1960 Oct;11:367–370. doi: 10.1177/000331976001100501. [DOI] [PubMed] [Google Scholar]
  2. KWAAN H. C., MCFADZEAN A. J. On plasma fibrinolytic activity induced by ischaemia. Clin Sci. 1956 May;15(2):245–257. [PubMed] [Google Scholar]
  3. OGSTON D., FULLERTON H. W. Changes in fibrinolytic activity produced by physical activity. Lancet. 1961 Sep 30;2(7205):730–733. doi: 10.1016/s0140-6736(61)90685-7. [DOI] [PubMed] [Google Scholar]
  4. SHERRY S., LINDEMEYER R. I., FLETCHER A. P., ALKJAERSIG N. Studies on enhanced fibrinolytic activity in man. J Clin Invest. 1959 May;38(5):810–822. doi: 10.1172/JCI103863. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. TODD A. S. The histological localisation of fibrinolysin activator. J Pathol Bacteriol. 1959 Jul;78:281–283. doi: 10.1002/path.1700780131. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES