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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1977 Jul;30(7):606–608. doi: 10.1136/jcp.30.7.606

Comparison of coagulase, deoxyribonuclease (DNase), and heat-stable nuclease tests for identification of Staphylococcus aureus.

R E Menzies
PMCID: PMC476495  PMID: 328535

Abstract

One thousand and thirty-five clinical isolates of the genus staphylococcus were used to compare the coagulase test with the deoxyribonuclease (DNase) and heat-stable nuclease tests as methods for identifying Staphylococcus aureus. Conflicting results were obtained with 65 isolates when the coagulase test was compared with the DNase test but with only one isolate when the coagulase test was compared with the heat-stable nuclease test. The heat-stable nuclease test produced reliable results after four hours' incubation and was considered a satisfactory substitute for the coagulase test in the clinical laboratory.

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Selected References

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