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. 1977 Sep;30(9):851–856. doi: 10.1136/jcp.30.9.851

Two cases of monoclonal immunoglobulins with antistreptolysin activity: clinical and laboratory study.

F A Lustermans, F Klein
PMCID: PMC476574  PMID: 915012

Abstract

In two patients with a persisting, high antistreptolysin titre the antistreptolysin activity in both cases resided exclusively in a monoclonal IgG component in the serum. This component had all the characteristics of a true antibody. A history in both patients of arthritis with or without angina suggested that the monoclonal antibodies were reactive in origin, although definite proof was lacking. In one case there was a suggestion of incipient myeloma. Whenever an extremely high antistreptolysin titre persists after antibiotic treatment the possibility of paraproteinaemia should be considered.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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