Abstract
The effects of acute fat feeding on fibrinolytic activity, platelet aggregation, and Stypven time in 10 Africans and 10 Asians are presented and compared with the results previously obtained in 10 Europeans.
These indicated that the inhibition of fibrinolytic activity seen in Europeans does not occur in either Africans or Asians although the Stypven time was shortened in all three groups.
Platelet aggregation, as measured by the Chandler's tube technique, was inhibited by fat feeding in Europeans but was unchanged in Africans and Asians.
The results also indicate that the fibrinolytic activity of Africans and Asians is greater than that of Europeans.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ALKJAERSIG N., FLETCHER A. P., SHERRY S. The mechanism of clot dissolution by plasmin. J Clin Invest. 1959 Jul;38(7):1086–1095. doi: 10.1172/JCI103885. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dubber A. H., Rifkind B., Gale M., McNicol G. P., Douglas A. S. The effect of fat feeding on fibrinolysis, "Stypven" time and platelet aggregation. J Atheroscler Res. 1967 Mar-Apr;7(2):225–235. doi: 10.1016/s0368-1319(67)80083-8. [DOI] [PubMed] [Google Scholar]
- MACLAGAN N. F., BILLIMORIA J. D., CURTIS C. Lipaemia and blood coagulation with special reference to the Stypven technique. Lancet. 1958 Oct 25;2(7052):865–869. doi: 10.1016/s0140-6736(58)92302-x. [DOI] [PubMed] [Google Scholar]
- MCNICOL G. P., GALE S. B., DOUGLAS A. S. In-vitro and in-vivo studies of a preparation of urokinase. Br Med J. 1963 Apr 6;1(5335):909–915. doi: 10.1136/bmj.1.5335.909. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Menon I. S. Fibrinolytic activity in the blood of 99 healthy young British, African and Asian subjects. Lab Pract. 1968 Feb;17(2):194–passim. [PubMed] [Google Scholar]
- Menon I. S. Fibrinolytic activity in the blood of Nigerian students after four years' residence in the United Kingdom. Lab Pract. 1967 May;16(5):574–577. [PubMed] [Google Scholar]
- RATNOFF O. D., MENZIE C. A new method for the determination of fibrinogen in small samples of plasma. J Lab Clin Med. 1951 Feb;37(2):316–320. [PubMed] [Google Scholar]
- REMMERT L. F., COHEN P. P. Partial purification and properties of a proteolytic enzyme of human serum. J Biol Chem. 1949 Nov;181(1):431–448. [PubMed] [Google Scholar]
- SHERRY S., ALKJAERSIG N. Studies on the fibrinolytic enzyme of human plasma. Thromb Diath Haemorrh. 1957 Aug 15;1(2):264–288. [PubMed] [Google Scholar]
- SHERRY S., LINDEMEYER R. I., FLETCHER A. P., ALKJAERSIG N. Studies on enhanced fibrinolytic activity in man. J Clin Invest. 1959 May;38(5):810–822. doi: 10.1172/JCI103863. [DOI] [PMC free article] [PubMed] [Google Scholar]
- VAN HANDEL E., ZILVERSMIT D. B. Micromethod for the direct determination of serum triglycerides. J Lab Clin Med. 1957 Jul;50(1):152–157. [PubMed] [Google Scholar]