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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1970 Oct;23(7):604–607. doi: 10.1136/jcp.23.7.604

Cellular contamination during automatic and manual staining of cytological smears

W T Barr 1, D E B Powell 1, J B Raffan 1
PMCID: PMC476845  PMID: 4098417

Abstract

Three routine cervical smears were contaminated with adenocarcinoma cells from a malignant serous effusion which was being processed simultaneously in an automatic staining machine. Further investigation showed that cells were transferred in up to 17% of cases. However, with manual staining, the figure could be as high as 30%. The possibility of misleading cellular transfer should therefore always be considered. Serious fluids should not be processed with routine cervical smears.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cremer A. W. Automatic slide staining in clinical bacteriology. J Med Lab Technol. 1968 Oct;25(4):387–390. [PubMed] [Google Scholar]

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