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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1970 Nov;23(8):690–694. doi: 10.1136/jcp.23.8.690

Lymphocytic sialadenitis in the major and minor glands: a correlation in postmortem subjects

D M Chisholm 1,2, J P Waterhouse 1,2, D K Mason 1,2
PMCID: PMC476869  PMID: 5488040

Abstract

In the present investigation, the prevalence of focal lymphocytic adenitis in the submandibular salivary gland was observed in a series of 116 postmortem subjects after suitable exclusions had been made. Focal lymphocytic adenitis could not be demonstrated in the labial salivary glands. The degree of lymphocytic infiltration in the labial salivary glands is positively correlated with the level of focal lymphocytic adenitis in the submandibular glands in the same subject. Lymphocytic foci and lymphocytic infiltrations found under these circumstances are probably related. This finding provides conceptual support for the examination, by biopsy, of the labial glands in patients suspected of Sjögren's syndrome.

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Selected References

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  1. Chisholm D. M., Mason D. K. Labial salivary gland biopsy in Sjögren's disease. J Clin Pathol. 1968 Sep;21(5):656–660. doi: 10.1136/jcp.21.5.656. [DOI] [PMC free article] [PubMed] [Google Scholar]
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