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. 1971 Apr;24(3):259–262. doi: 10.1136/jcp.24.3.259

Use of plasma instead of serum in laboratory tests for infectious mononucleosis

R J L Davidson 1, S R Main 1
PMCID: PMC476965  PMID: 4995569

Abstract

Until recently, the exclusive use of serum in all laboratory tests for detecting heterophile antibody has remained unquestioned. This communication describes a series of studies which demonstrate that comparable results are obtained when sequestrenized plasma is used instead of serum in the conventional differential absorption technique and in two slide screening tests. It is confirmed that significant differences in the final differential absorption titres can result from variations in the agglutinability of erythrocytes from different sheep but such differences when present are the same for plasma as for serum. The advantages of using plasma for routine purposes are briefly discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Lee C. L., Davidsohn I., Panczyszyn O. Horse agglutinins in infectious mononucleosis. II. The spot test. Am J Clin Pathol. 1968 Jan;49(1):12–18. doi: 10.1093/ajcp/49.1.12. [DOI] [PubMed] [Google Scholar]
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