Table 1. Case distribution according to the AML FAB classification and phenotypical analysis by flow cytometry with respect to CD97 expression.
| CD97 neg | CD97 pos | ||||
|---|---|---|---|---|---|
| number | percent | number | percent | P value | |
| patients | 177 | 208 | |||
| AML M0-2 | 141 | 79 | 131 | 63 | 0.0005 |
| AML M3 | 0 | 0 | 16 | 8 | <0.001 |
| AML M4/5 | 34 | 19 | 57 | 27 | 0.0709 |
| AML M6/7 | 2 | 1 | 4 | 2 | ns |
| CD34+ | 138/177 | 78 | 109/208 | 52 | <0.001 |
| CD13+ | 153/165 | 93 | 179/192 | 93 | ns |
| CD33+ | 159/177 | 94 | 193/198 | 97 | 0.0756 |
| CD117+ | 166/171 | 97 | 180/199 | 90 | 0.0107 |
| HLA-DR+ | 149/165 | 90 | 166/192 | 86 | ns |
| CD56+ | 62/178 | 35 | 62/208 | 30 | ns |
| CD2+ and/or CD7+ | 21/178 | 12 | 21/208 | 10 | ns |
| 7.1+ | 11 | 6 | 15 | 7 | ns |
| mNPM | 25/167 | 15 | 71/193 | 37 | <0.001 |
| mFLT3 | 17/164 | 10 | 73/194 | 38 | <0.001 |
| good risk genetics | 11/164 | 7 | 33/194 | 17 | 0.0035 |
| mNPM only | 16/167 | 10 | 32/193 | 17 | 0.0619 |
Abbreviations. ns: not significant; m: mutated; neg: negative; pos: positive