Abstract
Twelve out of 14 strains of Pseudomonas pseudomallei were inhibited in vitro by a combination of trimethoprim 1 μg per ml and sulphamethoxazole 20 μg per ml or by lower concentrations. Of the remaining strains, one was marginally more resistant and one was distinctly so. In tests utilizing two of the sensitive strains, inhibitory concentrations of the individual drugs exerted a bactericidal effect when combined.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bushby S. R., Hitchings G. H. Trimethoprim, a sulphonamide potentiator. Br J Pharmacol Chemother. 1968 May;33(1):72–90. doi: 10.1111/j.1476-5381.1968.tb00475.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Darrell J. H., Garrod L. P., Waterworth P. M. Trimethoprim: laboratory and clinical studies. J Clin Pathol. 1968 Mar;21(2):202–209. doi: 10.1136/jcp.21.2.202. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Eickhoff T. C., Bennett J. V., Hayes P. S., Feeley J. Pseudomonas pseudomallei: susceptibility to chemotherapeutic agents. J Infect Dis. 1970 Feb;121(2):95–102. doi: 10.1093/infdis/121.2.95. [DOI] [PubMed] [Google Scholar]
- Grunberg E., Beskid G., Delorenzo W. F., Titsworth E. Activity of selected antimicrobial agents against the Pseudmonas pseudomallei infection of mice. Am Rev Respir Dis. 1970 Apr;101(4):623–626. doi: 10.1164/arrd.1970.101.4.623. [DOI] [PubMed] [Google Scholar]
- Jenkins G. C., Hughes D. T., Hall P. C. A haematological study of patients receiving long-term treatment with trimethoprim and sulphonamide. J Clin Pathol. 1970 Jul;23(5):392–396. doi: 10.1136/jcp.23.5.392. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MAEGRAITH B. G., LEITHEAD C. S. MELIOIDOSIS: A CASE-REPORT. Lancet. 1964 Apr 18;1(7338):862–863. doi: 10.1016/s0140-6736(64)91581-8. [DOI] [PubMed] [Google Scholar]
- Malizia W. F., West G. A., Brundage W. G., Walden D. C. Melioidosis-laboratory studies. Health Lab Sci. 1969 Jan;6(1):27–39. [PubMed] [Google Scholar]
- Morrison I. M. Chronic melioidosis. Proc R Soc Med. 1970 Mar;63(3):289–290. [PMC free article] [PubMed] [Google Scholar]
- Peterson T. A., Ruiz E. The case of the tussive thief. JAMA. 1968 Apr 8;204(2):176–177. [PubMed] [Google Scholar]
- Spotnitz M., Rudnitzky J., Rambaud J. J. Melioidosis pneumonitis. Analysis of nine cases of a benign form of melioidosis. JAMA. 1967 Dec 4;202(10):950–954. doi: 10.1001/jama.202.10.950. [DOI] [PubMed] [Google Scholar]
- Thin R. N., Brown M., Stewart J. B., Garrett C. J. Melioidosis: a report of ten cases. Q J Med. 1970 Jan;39(153):115–127. [PubMed] [Google Scholar]