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. 1971 Dec;24(9):831–836. doi: 10.1136/jcp.24.9.831

Lysosomal enzyme cytochemistry in acute leukaemia

J R Mann 1, J S Simpson 1, R M Munkley 1, J Stuart 1
PMCID: PMC477194  PMID: 4110790

Abstract

A cytochemical study of the lysosomal enzyme β-glucuronidase in 60 cases of acute leukaemia has shown a qualitative difference in the cytoplasmic distribution of the enzyme between blast cells of the lymphoid and myeloid cell series. This difference provides a useful additional method for cytochemical classification of cell type and is superior in this respect to the other lysosomal enzymes studied (aryl sulphatase and acid phosphatase). The β-glucuronidase reaction is recommended in those cases of acute leukaemia in which the periodic acid-Schiff reaction is negative or equivocal.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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