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. 2016 Mar;147(3):289. doi: 10.1085/jgp.20151143701262016c

Correction: Orai1 pore residues control CRAC channel inactivation independently of calmodulin

Franklin M Mullins, Michelle Yen, Richard S Lewis
PMCID: PMC4772371  PMID: 26880755

Volume 147, No. 2, February 1, 2016. Pages 137–152.

The Journal of General Physiology regrets mistakes that appeared in the original publication of this paper, as the result of production errors. The equation in the first paragraph of Materials and methods section Data analysis did not include τ1. The paragraph with the corrected equation reads as “The time course of Orai1 current inactivation was fitted with the biexponential function I = I 0 + A 1 e t/τ1 + A 2 e t/τ2, where I is current, I 0 is the steady-state current, A 1 and A 2 are amplitudes, and τ1 and τ2 are inactivation time constants.”

Also, Fig. 6 B was originally published with three traces instead of four traces. The corrected file appears below.

Figure 6.

Figure 6.

CRAC channel CDI phenotypes for mutations of the triple basic ring. All currents were recorded as described in Fig. 3. Representative currents are shown for WT Orai1 (A, same traces shown in Fig. 3 A), and Orai1 point mutants R83E (B), R83N (C), K87E (D), and R91E (E), with the extent of CDI summarized in F. Each point represents the mean ± SEM for n = 6–10 cells.

The HTML and PDF versions of this article have been changed to reflect these corrections.


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