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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1972 Mar;25(3):210–217. doi: 10.1136/jcp.25.3.210

Aggregation of human platelets by commercial preparations of bovine and porcine antihaemophilic globulin

C D Forbes 1, R D Barr 1, G P McNicol 1, A S Douglas 1,1
PMCID: PMC477264  PMID: 5062992

Abstract

Infusion of commercial preparations of porcine and bovine antihaemophilic globulin into three haemophilic patients produced transient thrombocytopenia. This platelet-aggregating activity has been shown to be present in a wide range of animal plasmas and is related to the fibrinogen fraction. The mechanism of platelet aggregation by animal fibrinogen is discussed and some inhibitors of the reaction are described.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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