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. 1972 May;25(5):433–436. doi: 10.1136/jcp.25.5.433

Cross-reacting material in genetic variants of haemophilia B

Dominique Meyer 1,2, Ethel Bidwell 1,2, Marie José Larrieu 1,2
PMCID: PMC477341  PMID: 4114698

Abstract

Cross-reacting factor IX material (CRM) was immunologically detected in the plasma of 38 normal individuals and 21 out of 22 haemophilia B patients using a rabbit antibody to factor IX. The same reacting material was detected in only nine of these patients using a human antibody. These results indicate that the plasma of the majority of haemophilia B patients contains a protein-lacking biological activity but having antigenic determinants in common with normal factor IX.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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