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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1972 May;25(5):437–440. doi: 10.1136/jcp.25.5.437

A comparison of the absorbed fluorescent treponemal antibody (FTA-ABS) test and other screening tests for treponemal disease in patients attending a venereal disease clinic

A E Wilkinson 1, G Scrimgeour 1, P Rodin 1
PMCID: PMC477342  PMID: 4558249

Abstract

Screening tests—absorbed fluorescent treponemal (FTA-ABS), the Reiter protein complement-fixation (RPCFT), VDRL slide test, automated reagin—and cardiolipin Wassermann reaction—were carried out on 1922 consecutive new patients attending the Whitechapel Clinic over a three-month period.

Taking the FTA-ABS test results as an index, the most efficient combination of conventional tests was found to be the RPCFT and automated reagin test. The cardiolipin WR proved to be under-sensitive and of little value compared with the other tests.

Forty-two per cent of the 107 sera reactive in the FTA-ABS test were not detected by the RPCFT or ART tests. An assessment based on the TPI test results and clinical findings in these patients is presented.

The scope and limitations of the FTA-ABS test as a screening procedure are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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