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. 1972 Sep;25(9):789–792. doi: 10.1136/jcp.25.9.789

Serum protein levels in primary biliary cirrhosis

R N M MacSween 1,2, C H W Horne 1,2, Anne J Moffat 1,2, Hazel M Hughes 1,2
PMCID: PMC477512  PMID: 5086222

Abstract

Serum levels of albumin, transferrin, α2-macroglobulin, β1C/β1A, IgA, IgG, and IgM have been determined in 73 patients with primary biliary cirrhosis and in age- and sex-matched controls. A highly significant fall in albumin was demonstrated, and there were highly significant increases in α2-macroglobulin and all three immunoglobulin levels. Transferrin and β1/Cβ1A levels were unchanged. No significant correlations were found between the titre of antimitochondrial antibody, the duration of symptoms, and any of the serum proteins estimated. A highly significant positive correlation was present between serum albumin and transferrin levels in both patient and control groups.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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