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. 1972 Dec;25(12):1056–1062. doi: 10.1136/jcp.25.12.1056

Spicular arrangement of amyloid in renal biopsy

I D Ansell 1,2,1, A M Joekes 1,2
PMCID: PMC477620  PMID: 4120571

Abstract

A spicular arrangement of amyloid on the epithelial aspect of the glomerular basement membrane has been seen to a variable degree in silver-stained sections of renal biopsies in eight of 38 patients with amyloidosis. Electron microscopical examination revealed a spectrum of appearances of the amyloid fibrils which would account for this finding. Only two of these eight patients had amyloidosis secondary to chronic infection, a much lower proportion than in the group as a whole. The possibility of confusion with membranous nephropathy is discussed with relevance to possible modes of treatment.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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