Abstract
Group-specific polysaccharides of Neisseria meningitidis groups A and C have been demonstrated by means of a rapid, sensitive slide agglutination test with latex particles coated with antibodies. In this manner, the diagnosis can be made from the cerebrospinal fluid of patients with meningococcal meningitis caused by serogroups A or C even when the culture is negative. The method appears to be more sensitive than countercurrent immunoelectrophoresis and less elaborate.
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- Abbott J. D., Graves J. F. Serotype and sulphonamide sensitivity of meningococci isolated from 1966 to 1971. J Clin Pathol. 1972 Jun;25(6):528–530. doi: 10.1136/jcp.25.6.528. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Alexander H. E. PROGNOSTIC VALUE OF THE PRECIPITIN TEST IN MENINGOCOCCUS MENINGITIS. J Clin Invest. 1937 Mar;16(2):207–211. doi: 10.1172/JCI100849. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BLOOMFIELD N., GORDON M. A., ELMENDORF D. F., Jr DETECTION OF CRYPTOCOCCUS NEOFORMANS ANTIGEN IN BODY FLUIDS BY LATEX PARTICLE AGGLUTINATION. Proc Soc Exp Biol Med. 1963 Oct;114:64–67. doi: 10.3181/00379727-114-28586. [DOI] [PubMed] [Google Scholar]
- Edwards E. A. Immunologic investigations of meningococcal disease. I. Group-specific Neisseria meningitidis antigens present in the serum of patients with fulminant meningococcemia. J Immunol. 1971 Feb;106(2):314–317. [PubMed] [Google Scholar]
- Goodman J. S., Kaufman L., Koenig M. G. Diagnosis of cryptococcal meningitis. Value of immunologic detection of cryptococcal antigen. N Engl J Med. 1971 Aug 19;285(8):434–436. doi: 10.1056/NEJM197108192850804. [DOI] [PubMed] [Google Scholar]
- Gotschlich E. C., Liu T. Y., Artenstein M. S. Human immunity to the meningococcus. 3. Preparation and immunochemical properties of the group A, group B, and group C meningococcal polysaccharides. J Exp Med. 1969 Jun 1;129(6):1349–1365. doi: 10.1084/jem.129.6.1349. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Greenwood B. M., Whittle H. C., Dominic-Rajkovic O. Counter-current immunoelectrophoresis in the diagnosis of meningococcal infections. Lancet. 1971 Sep 4;2(7723):519–521. doi: 10.1016/s0140-6736(71)90439-9. [DOI] [PubMed] [Google Scholar]
- Newman R. B., Stevens R. W., Gaafar H. A. Latex agglutination test for the diagnosis of Haemophilus influenzae meningitis. J Lab Clin Med. 1970 Jul;76(1):107–113. [PubMed] [Google Scholar]
- Robinson J. A., Apicella M. A. Isolation and Characterization of Neisseria meningitidis Groups A, C, X, and Y Polysaccharide Antigens. Infect Immun. 1970 Jan;1(1):8–14. doi: 10.1128/iai.1.1.8-14.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]