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. 1973 Jan;26(1):7–16. doi: 10.1136/jcp.26.1.7

Genus-specific leptospiral antigen and its possible use in laboratory diagnosis

A Palit 1, J Gulasekharam 1
PMCID: PMC477641  PMID: 4632761

Abstract

Sheep red cells, sensitized with a genus-specific leptospiral substance extracted from a water leptospira, were preserved by freeze drying. The serological reactivity of the preparation was tested against a total of 41 sera from proven cases of human leptospirosis and 27 from proven cases of animal leptospirosis. The sensitized, freeze-dried red cells appeared to be a sensitive reagent for the detection of leptospiral antibodies by haemagglutination. The use of this reagent as a screening test for leptospiral diagnosis is discussed. In the reported haemagglutination test on human and rabbit antisera the findings suggested that only IgM (19S) antibodies took part in the reaction.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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