Skip to main content
NCBI home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1973 Jan;26(1):21–24. doi: 10.1136/jcp.26.1.21

Frequency of intraendothelial `virus-like' particles: An electron microscopy study of 376 human renal biopsies

J Bariéty 1, D Richer 1, M D Appay 1, J Grossetete 1, P Callard 1
PMCID: PMC477643  PMID: 4348403

Abstract

Intraendothelial `virus-like' particles were found in all cases requiring a renal biopsy: in 89% of patients with systemic lupus erythematosus (SLE), in 73% of those receiving renal transplants more than one year before, and in 24·5% of all other renal biopsies.

Full text

PDF
21

Images in this article

22Image
on p.22

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bariety J., Amor B., Kahan A., Balafrej J. L., Delbarre F. Ultrastructural anomalies in mononuclear cells of peripheral blood in S.L.E.: Presence of virus-like inclusions. Rev Eur Etud Clin Biol. 1971 Aug-Sep;16(7):715–720. [PubMed] [Google Scholar]
  2. Bariéty J., Druet P., Lagrue G., Samarcq P., Milliez P. Les glomérulopathies "extra-membraneuses" (G.E.M.). Etude morphologique en microscopie optique, électronique et en immunofluorescence. Pathol Biol (Paris) 1970 Jan;18(1):5–32. [PubMed] [Google Scholar]
  3. Bariéty J., Milliez P. Inclusions d'aspect "viral" dans le rein des lupus érythémateux disséminés. Bull Acad Natl Med. 1970 Apr 14;154(13):249–252. [PubMed] [Google Scholar]
  4. Bloodworth J. M., Jr, Shelp W. D. Endothelial cytoplasmic inclusions. Arch Pathol. 1970 Sep;90(3):252–258. [PubMed] [Google Scholar]
  5. Chandra S. Undulating tubules associated with endoplasmic reticulum in pathologic tissues. Lab Invest. 1968 Apr;18(4):422–428. [PubMed] [Google Scholar]
  6. Eknoyan G., Györkey F., Dichoso C., Martinez-Maldonado M., Suki W. N., Györkey P. Renal morphological and immunological changes associated with acute viral hepatitis. Kidney Int. 1972 Jun;1(6):413–419. doi: 10.1038/ki.1972.54. [DOI] [PubMed] [Google Scholar]
  7. Feorino P. M., Hierholzer J. C., Norton W. L. Viral isolation studies of inclusion positive biopsy from human connective tissue diseases. Arthritis Rheum. 1970 Jul-Aug;13(4):378–380. doi: 10.1002/art.1780130403. [DOI] [PubMed] [Google Scholar]
  8. Garancis J. C., Komorowski R. A., Bernhard G. C., Straumfjord J. V. Significance of cytoplasmic microtubules in lupus nephritis. Am J Pathol. 1971 Jul;64(1):1–12. [PMC free article] [PubMed] [Google Scholar]
  9. Grausz H., Earley L. E., Stephens B. G., Lee J. C., Hopper J., Jr Diagnostic import of virus-like particles in the glomerular endothelium of patients with systemic lupus erythematosus. N Engl J Med. 1970 Sep 3;283(10):506–511. doi: 10.1056/NEJM197009032831003. [DOI] [PubMed] [Google Scholar]
  10. Györkey F., Min K. W., Sincovics J. G., Györkey P. Systemic lupus erythematosus and myxovirus. N Engl J Med. 1969 Feb 6;280(6):333–333. doi: 10.1056/nejm196902062800620. [DOI] [PubMed] [Google Scholar]
  11. Györkey F., Sinkovics J. G. Microtubules of systemic lupus erythematosus. Lancet. 1971 Jan 16;1(7690):131–132. doi: 10.1016/s0140-6736(71)90859-2. [DOI] [PubMed] [Google Scholar]
  12. Györkey F., Sinkovics J. G., Min K. W., Györkey P. A morphologic study on the occurrence and distribution of structures resembling viral nucleocapsids in collagen diseases. Am J Med. 1972 Aug;53(2):148–158. doi: 10.1016/0002-9343(72)90125-8. [DOI] [PubMed] [Google Scholar]
  13. Hollinger F. B., Sharp J. T., Lidsky M. D., Rawls W. E. Antibodies to viral antigens in systemic lupus erythematosus. Arthritis Rheum. 1971 Jan-Feb;14(1):1–11. doi: 10.1002/art.1780140102. [DOI] [PubMed] [Google Scholar]
  14. Hurd E. R., Eigenbrodt E., Worthen H., Strunk S. S., Ziff M. Glomerular cytoplasmic tubular structures in renal biopsies of patients with systemic lupus erythematosus and other diseases. Arthritis Rheum. 1971 Jul-Aug;14(4):539–550. doi: 10.1002/art.1780140414. [DOI] [PubMed] [Google Scholar]
  15. Kawano K., Miller L., Kimmelstiel P. Virus-like structures in lupus erythematosus. N Engl J Med. 1969 Nov 27;281(22):1228–1229. doi: 10.1056/NEJM196911272812207. [DOI] [PubMed] [Google Scholar]
  16. Moses H. L., Glade P. R., Kasel J. A., Rosenthal A. S., Hirshaut Y., Chessin L. N. Infectious mononucleosis: detection of herpeslike virus and reticular aggregates of small cytoplasmic particles in continuous lymphoid cell lines derived from peripheral blood. Proc Natl Acad Sci U S A. 1968 Jun;60(2):489–496. doi: 10.1073/pnas.60.2.489. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Norton W. L. Endothelial inclusions in active lesions of systemic lupus erythematosus. J Lab Clin Med. 1969 Sep;74(3):369–379. [PubMed] [Google Scholar]
  18. Phillips P. E., Christian C. L. Myxovirus antibody increases in human connective tissue disease. Science. 1970 May 22;168(3934):982–984. doi: 10.1126/science.168.3934.982. [DOI] [PubMed] [Google Scholar]
  19. Pincus T., Blacklow N. R., Grimley P. M., Bellanti J. A. Glomerular microtubules of systemic lupus erythematosus. Lancet. 1970 Nov 21;2(7682):1058–1061. doi: 10.1016/s0140-6736(70)90287-4. [DOI] [PubMed] [Google Scholar]
  20. Prunieras M., Grupper C., Durepaire R., Beltzer-Garelly E., Regnier M. Etude ultrastructurale de la peau dans 42 cas de lupus érythémateux. Presse Med. 1970 Dec 26;78(55):2475–2479. [PubMed] [Google Scholar]
  21. Recher L., Sinkovics J. G., Sykes J. A., Whitescarver J. Electron microscopic studies of suspension cultures derived from human leukemic and nonleukemic sources. Cancer Res. 1969 Feb;29(2):271–285. [PubMed] [Google Scholar]
  22. Schumacher H. R., Jr Tubular paramyxovirus-like structures in synovial vascular endothelium. Ann Rheum Dis. 1970 Jul;29(4):445–447. doi: 10.1136/ard.29.4.445. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Tisher C. C., Kelso H. B., Robinson R. R., Gunnells J. C., Burkholder P. M. Intraendothelial inclusions in kidneys of patients with systemic lupus erythematosus. Ann Intern Med. 1971 Oct;75(4):537–547. doi: 10.7326/0003-4819-75-4-537. [DOI] [PubMed] [Google Scholar]
  24. Uzman B. G., Saito H., Kasac M. Tubular arrays in the endoplasmic reticulum in human tumor cells. Lab Invest. 1971 Jun;24(6):492–498. [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES