Skip to main content
PMC home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1973 Oct;26(10):731–737. doi: 10.1136/jcp.26.10.731

An outbreak of infantile gastroenteritis due to E. coli 0142

D H Kennedy 1,2,3,4, G H Walker 1,2,3,4, R J Fallon 1,2,3,4, J F Boyd 1,2,3,4, R J Gross 1,2,3,4, B Rowe 1,2,3,4
PMCID: PMC477872  PMID: 4584347

Abstract

Twelve cases of gastroenteritis caused by Escherichia coli 0142K86H6 are described. Ten of these cases were clearly involved in an outbreak of cross infection. The other two cases yielded interesting information on infection with E. coli. 0142. Five cases, two being fatal, required repeated intravenous infusion, and one further infant required parenteral replacement therapy on a single occasion only. Cross infection occurred at the primary site—a ward partitioned into cubicles—despite full barrier nursing techniques. Infection spread also to two other wards, and resulted from transfer of latently infected cases. Illness in several infants was protracted and debilitating because of the relapsing nature of the infection. The pathology of the two fatalities is reported briefly.

Full text

PDF
731

Images in this article

734Image
on p.734
735Image
on p.735
735Image
on p.735
736Image
on p.736

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ironside A. G., Brennand J., Mandal B. K., Heyworth B. Cross-infection in infantile gastroenteritis. Arch Dis Child. 1971 Dec;46(250):815–818. doi: 10.1136/adc.46.250.815. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Jacobs S. I., Holzel A., Wolman B., Keen J. H., Miller V., Taylor J., Gross R. J. Outbreak of infantile gastro-enteritis caused by Escherichia coli O114. Arch Dis Child. 1970 Oct;45(243):656–663. doi: 10.1136/adc.45.243.656. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Love W. C., Gordon A. M. E. coli O142 gastroenteritis in Scotland. Lancet. 1971 Apr 24;1(7704):861–861. doi: 10.1016/s0140-6736(71)91533-9. [DOI] [PubMed] [Google Scholar]
  4. Love W. C., Gordon A. M., Gross R. J., Rowe B. Infantile gastroenteritis due to Escherichia coli 0142. Lancet. 1972 Aug 19;2(7773):355–357. doi: 10.1016/s0140-6736(72)91738-2. [DOI] [PubMed] [Google Scholar]
  5. MCKAY D. G., WAHLE G. H., Jr Epidemic gastroenteritis due to Escherichia coli O111 B4. II. Pathologic anatomy, with special reference of the presence of the local and generalized Shwartzman phenomena. AMA Arch Pathol. 1955 Dec;60(6):679–693. [PubMed] [Google Scholar]
  6. OLARTE J., RAMOS-ALVAREZ M. EPIDEMIC DIARRHEA IN PREMATURE INFANTS. ETIOLOGICAL SIGNIFICANCE OF A NEWLY RECOGNIZED TYPE OF ESCHERICHIA COLI (0142:K86(B):H6). Am J Dis Child. 1965 May;109:436–438. [PubMed] [Google Scholar]
  7. ORSKOV F., ORSKOV I., REES T. A., SAHAB K. Two new E. coli O-antigens: 0141 and 0142 and two new coli K-antigens: K85 and K86. Acta Pathol Microbiol Scand. 1960;48:48–50. doi: 10.1111/j.1699-0463.1960.tb04736.x. [DOI] [PubMed] [Google Scholar]
  8. ROZANSKY R., ROSENMANN E., BEN-ARI Y., STERK V. V. ENTEROPATHOGENIC ESCHERICHIA COLI INFECTIONS IN INFANTS DURING THE PERIOD FROM 1957 TO 1962. J Pediatr. 1964 Apr;64:521–527. doi: 10.1016/s0022-3476(64)80341-3. [DOI] [PubMed] [Google Scholar]
  9. Rho Y. M., Josephson J. E. Epidemic enteropathogenic Escherichia coli, Newfoundland, 1963: autopsy study of 16 cases. Can Med Assoc J. 1967 Feb 18;96(7):392–398. [PMC free article] [PubMed] [Google Scholar]
  10. Roberts W., Shrivastava S. C., Emslie J. A., Ingham H. R. E. Coli 0142 and infantile enteritis in Scotland. Lancet. 1971 Apr 10;1(7702):757–758. doi: 10.1016/s0140-6736(71)92032-0. [DOI] [PubMed] [Google Scholar]
  11. Ronald A. R., Turck M., Petersdorf R. G. A critical evaluation of nalidixic acid in urinary-tract infections. N Engl J Med. 1966 Nov 17;275(20):1081–1089. doi: 10.1056/NEJM196611172752001. [DOI] [PubMed] [Google Scholar]
  12. Rowe B., Gross R. J. E. coli O 142 and infantile enteritis in Scotland. Lancet. 1971 Mar 27;1(7700):649–650. doi: 10.1016/s0140-6736(71)91582-0. [DOI] [PubMed] [Google Scholar]
  13. TAYLOR J., POWELL B. W., WRIGHT J. Infantile diarrhoea and vomiting; a clinical and bacteriological investigation. Br Med J. 1949 Jul 16;2(4619):117–125. doi: 10.1136/bmj.2.4619.117. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES