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. 1973 Oct;26(10):760–763. doi: 10.1136/jcp.26.10.760

Detection of fibrinogen antigens with two latex techniques applied to urine concentrates

Maria Benedetta Donati 1,2, N Semeraro 1,3, J Vermylen 1
PMCID: PMC477877  PMID: 4201501

Abstract

Fibrinogen antigens were measured either with an agglutination inhibition method (using latex particles coated with fibrinogen; Diagen test) or with a direct agglutination technique (using latex particles coated with a mixture of anti-D and anti-E antibodies; Thrombo-Wellcotest). Both methods were compared with the tanned red cell haemagglutination inhibition immunoassay (TRCHII) during progressive degradation of fibrinogen with plasmin and using purified fibrinogen fragments or urine concentrates from chronic glomerulonephritis or transplanted patients. Due to the different sensitivity of the two latex techniques to fibrinogen and its plasmin derivatives, their combined use may be helpful to distinguish the nature of the fibrinogen-like material excreted in urine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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