Abstract
The features of four cases of malignant haemangioendothelioma involving the liver and other organs are described. Two cases were associated with a microangiopathic haemolytic anaemia. The nature of the tumours and possible pathogenesis for the anaemias are discussed.
Full text
PDF







Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Alpert L. I., Benisch B. Hemangioendothelioma of the liver associated with microangiopathic hemolytic anemia. Report of four cases. Am J Med. 1970 May;48(5):624–628. doi: 10.1016/0002-9343(70)90013-6. [DOI] [PubMed] [Google Scholar]
- BAKER H. D., DAVSON J., PAGET G. E. Haemangio-endothelioma (Kupffer-cell sarcoma) of the liver. J Pathol Bacteriol. 1956 Jul;72(1):173–182. doi: 10.1002/path.1700720123. [DOI] [PubMed] [Google Scholar]
- BRAIN M. C., DACIE J. V., HOURIHANE D. O. Microangiopathic haemolytic anaemia: the possible role of vascular lesions in pathogenesis. Br J Haematol. 1962 Oct;8:358–374. doi: 10.1111/j.1365-2141.1962.tb06541.x. [DOI] [PubMed] [Google Scholar]
- BURSTON J. Kupffer cell sarcoma. Cancer. 1958 Jul-Aug;11(4):798–802. doi: 10.1002/1097-0142(195807/08)11:4<798::aid-cncr2820110418>3.0.co;2-p. [DOI] [PubMed] [Google Scholar]
- Bull B. S., Rubenberg M. L., Dacie J. V., Brain M. C. Microangiopathic haemolytic anaemia: mechanisms of red-cell fragmentation: in vitro studies. Br J Haematol. 1968 Jun;14(6):643–652. doi: 10.1111/j.1365-2141.1968.tb00370.x. [DOI] [PubMed] [Google Scholar]
- DA HORTA J. S. Late lesions in man caused by colloidal thorium dioxide (thorotrast); a new case of sarcoma of the liver twenty-two years after the injection. AMA Arch Pathol. 1956 Nov;62(5):403–418. [PubMed] [Google Scholar]
- Donald D., Dawson A. A. Microangiopathic haemolytic anaemia associated with malignant haemangio-endothelioma. J Clin Pathol. 1971 Jul;24(5):456–459. doi: 10.1136/jcp.24.5.456. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GILON E., RAMOT B., SHEBA C. Multiple hemangiomata associated with thrombocytopenia: remarks on the pathogenesis of the thrombocytopenia in this syndrome. Blood. 1959 Jan;14(1):74–79. [PubMed] [Google Scholar]
- GOOD T. A., CARNAZZO S. F., GOOD R. A. Thrombocytopenia and giant hemangioma in infants. AMA Am J Dis Child. 1955 Sep;90(3):260–274. doi: 10.1001/archpedi.1955.04030010262003. [DOI] [PubMed] [Google Scholar]
- Gibbs W. N., Connor R. C., Hutchison H. E. Malignant haemangio-endothelioma associated with thrombocytopenia. J Pathol Bacteriol. 1966 Jul;92(1):207–210. doi: 10.1002/path.1700920121. [DOI] [PubMed] [Google Scholar]
- Grampa G. Radiation injury with particular reference to thorotrast. Pathol Annu. 1971;6:147–169. [PubMed] [Google Scholar]
- Hopfner C., Dufour M., Pluot M., Caulet T. Hémangio-endothélio-sarcome splénique avec érythrophagocytose et angiopathie thrombotique. Etude morphologique, optique et ultrastructurale. Virchows Arch A Pathol Pathol Anat. 1972;356(1):66–75. [PubMed] [Google Scholar]
- KONTRAS S. B., GREEN O. C., KING L., DURAN R. J. Giant hemangioma with thrombocytopenia. Case report with survival and sequestration studies of platelets labeled with chromium 51. Am J Dis Child. 1963 Feb;105:188–195. [PubMed] [Google Scholar]
- Kwittken J., Tartow L. R. Haemochromatosis and Kupffer-cell sarcoma with unusual localisation of iron. J Pathol Bacteriol. 1966 Oct;92(2):571–573. doi: 10.1002/path.1700920237. [DOI] [PubMed] [Google Scholar]
- MacSween R. N., Vetters J. M., Ross S. K., Ferguson J., Johnstone J. M., Sandison A. T. Haemangio-endothelial sarcoma of the liver. J Pathol. 1973 Jan;109(1):39–44. doi: 10.1002/path.1711090105. [DOI] [PubMed] [Google Scholar]
- Regelson W., Kim U., Ospina J., Holland J. F. Hemangioendothelial sarcoma of liver from chronic arsenic intoxication by Fowler's solution. Cancer. 1968 Mar;21(3):514–522. doi: 10.1002/1097-0142(196803)21:3<514::aid-cncr2820210323>3.0.co;2-z. [DOI] [PubMed] [Google Scholar]
- Shanberge J. N., Tanaka K., Gruhl M. C. Chronic consumption coagulopathy due to hemangiomatous transformation of the spleen. Am J Clin Pathol. 1971 Dec;56(6):723–729. doi: 10.1093/ajcp/56.6.723. [DOI] [PubMed] [Google Scholar]
- Warner E. D., Hoak J. C., Fry G. L. Hemangioma, thrombocytopenia, and anemia. The Kasabach-Merritt syndrome in an animal model. Arch Pathol. 1971 Jun;91(6):523–528. [PubMed] [Google Scholar]








