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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1974 Apr;27(4):319–322. doi: 10.1136/jcp.27.4.319

Iodine contamination of the serum protein-bound iodine: Incidence and clinical significance

P R Pannall 1,2,3, P C Minnaar 1,2,3, A T Neser 1,2,3
PMCID: PMC478112  PMID: 4136836

Abstract

Iodine contamination as defined by the combination of a raised (PBI-T4I) difference and low 131I neck uptake was found in 38 (17·5%) of 217 euthyroid patients. Of these, 17 had PBI levels of greater than 20 μg/dl but in the remainder levels were clinically feasible. In only 21 was there a history of exposure to iodine. Two of 12 hypothyroid patients had PBI levels well within normal limits. False elevation of the PBI is thus shown to be common. It is neither always obvious nor can it be easily avoided. The PBI is not an acceptable alternative to T4 estimation by other methods.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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