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. 1974 Apr;27(4):326–329. doi: 10.1136/jcp.27.4.326

The effect of age on the fibrinolytic enzyme system

P J Hamilton 1,2, Audrey A Dawson 1,2, D Ogston 1,2, A S Douglas 1,2
PMCID: PMC478114  PMID: 4546946

Abstract

Components of the fibrinolytic enzyme system, FR-antigen and fibrinogen, were measured in 20 healthy volunteers aged 20-40 years and in 61 elderly subjects aged 66-96 years. Plasminogen activator levels did not significantly differ between the 20-40 and 66-75 age groups, but were higher in those over 75. Plasminogen showed no change with age except for a fall in those over 75. Fibrinogen, FR-antigen, α1-antitrypsin, and α2-macroglobulin all rose with age, but the mean fibrinogen concentration fell in the very elderly.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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