Skip to main content
PMC home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1974 May;27(5):341–347. doi: 10.1136/jcp.27.5.341

Identity of a newly isolated human polyomavirus from a patient with progressive multifocal leucoencephalopathy

Anne M Field 1,2, Sylvia D Gardner 1,2, R A Goodbody 1,2, M A Woodhouse 1,2,1
PMCID: PMC478123  PMID: 4368786

Abstract

Isolation of a strain of polyomavirus, designated COL, from the brain of a patient with progressive multifocal leucoencephalopathy is described. The COL strain is antigenically similar to JC polyomavirus, previously isolated from a brain affected by progressive multifocal leucoencephalopathy and is unrelated to BK, another human polyomavirus isolated from urine. Immunological cross testing of viruses in the Polyomavirus genus shows that there are at least six antigenic types in this group.

Full text

PDF
341

Images in this article

342Image
on p.342
343Image
on p.343
343Image
on p.343
343Image
on p.343
343Image
on p.343

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amako K., Mori R. Serological and morphological studies on progressive multifocal leucoencephalopathy virus. Jpn J Microbiol. 1972 Mar;16(2):155–158. doi: 10.1111/j.1348-0421.1972.tb00642.x. [DOI] [PubMed] [Google Scholar]
  2. Coleman D. V., Gardner S. D., Field A. M. Human polyomavirus infection in renal allograft recipients. Br Med J. 1973 Aug 18;3(5876):371–375. doi: 10.1136/bmj.3.5876.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Gardner S. D., Field A. M., Coleman D. V., Hulme B. New human papovavirus (B.K.) isolated from urine after renal transplantation. Lancet. 1971 Jun 19;1(7712):1253–1257. doi: 10.1016/s0140-6736(71)91776-4. [DOI] [PubMed] [Google Scholar]
  4. Gardner S. D. Prevalence in England of antibody to human polyomavirus (B.k.). Br Med J. 1973 Jan 13;1(5845):77–78. doi: 10.1136/bmj.1.5845.77. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Koch M. A., Becht H., Anderer F. A. Structure of simian virus 40. V. Localization of the C-type polypeptide chains. Virology. 1971 Jan;43(1):235–242. doi: 10.1016/0042-6822(71)90241-8. [DOI] [PubMed] [Google Scholar]
  6. Margalith M., Margalith E., Spira G. On the nature of the SV 40 viral antigen induced in BSC 1 transformed cells. Brief report. Arch Gesamte Virusforsch. 1972;36(3):398–400. doi: 10.1007/BF01249872. [DOI] [PubMed] [Google Scholar]
  7. Narayan O., Penney J. B., Jr, Johnson R. T., Herndon R. M., Weiner L. P. Etiology of progressive multifocal leukoencephalopathy. Identification of papovavirus. N Engl J Med. 1973 Dec 13;289(24):1278–1282. doi: 10.1056/NEJM197312132892405. [DOI] [PubMed] [Google Scholar]
  8. Newman J. T., Smith K. O. Characteristics of a swine papovavirus. Infect Immun. 1972 Jun;5(6):961–967. doi: 10.1128/iai.5.6.961-967.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Padgett B. L., Walker D. L. Prevalence of antibodies in human sera against JC virus, an isolate from a case of progressive multifocal leukoencephalopathy. J Infect Dis. 1973 Apr;127(4):467–470. doi: 10.1093/infdis/127.4.467. [DOI] [PubMed] [Google Scholar]
  10. Padgett B. L., Walker D. L., ZuRhein G. M., Eckroade R. J., Dessel B. H. Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet. 1971 Jun 19;1(7712):1257–1260. doi: 10.1016/s0140-6736(71)91777-6. [DOI] [PubMed] [Google Scholar]
  11. Penney J. B., Jr, Narayan O. Studies of the antigenic relationships of the new human papovaviruses by electron microscopy agglutination. Infect Immun. 1973 Aug;8(2):299–300. doi: 10.1128/iai.8.2.299-300.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Penney J. B., Jr, Weiner L. P., Herndon R. M., Narayan O., Johnson R. T. Virions from progressive multifocal leukoencephalopathy: rapid serological identification by electron microscopy. Science. 1972 Oct 6;178(4056):60–62. doi: 10.1126/science.178.4056.60. [DOI] [PubMed] [Google Scholar]
  13. Sack G. H., Jr, Narayan O., Danna K. J., Weiner L. P., Nathans D. The nucleic acid of an SV40-like virus isolated from a patient with progressive multifocal leukoencephalopathy. Virology. 1973 Feb;51(2):345–350. doi: 10.1016/0042-6822(73)90433-9. [DOI] [PubMed] [Google Scholar]
  14. Shah K. V. Evidence for an SV40-related papovavirus infection of man. Am J Epidemiol. 1972 Mar;95(3):199–206. doi: 10.1093/oxfordjournals.aje.a121387. [DOI] [PubMed] [Google Scholar]
  15. Shein H. M. Propagation of human fetal spongioblasts and astrocytes in dispersed cell cultures. Exp Cell Res. 1965 Dec;40(3):554–569. doi: 10.1016/0014-4827(65)90234-x. [DOI] [PubMed] [Google Scholar]
  16. Weiner L. P., Herndon R. M., Narayan O., Johnson R. T., Shah K., Rubinstein L. J., Preziosi T. J., Conley F. K. Isolation of virus related to SV40 from patients with progressive multifocal leukoencephalopathy. N Engl J Med. 1972 Feb 24;286(8):385–390. doi: 10.1056/NEJM197202242860801. [DOI] [PubMed] [Google Scholar]
  17. Weiner L. P., Narayan O., Penney J. B., Jr, Herndon R. M., Feringa E. R., Tourtellotte W. W., Johnson R. T. Papovavirus of JC type in progressive multifocal leukoencephalopathy. Rapid identification and subsequent isolation. Arch Neurol. 1973 Jul;29(1):1–3. doi: 10.1001/archneur.1973.00490250019001. [DOI] [PubMed] [Google Scholar]
  18. ZURHEIN G., CHOU S. M. PARTICLES RESEMBLING PAPOVA VIRUSES IN HUMAN CEREBRAL DEMYELINATING DISEASE. Science. 1965 Jun 11;148(3676):1477–1479. doi: 10.1126/science.148.3676.1477. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES