Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1974 May;27(5):353–355. doi: 10.1136/jcp.27.5.353

Increased incidence of HL-A 1 and 8 in patients showing IgG or complement coating on their red cells

J A G Da Costa 1,2, A G White 1,2, A C Parker 1,2, G B Grigor 1,2
PMCID: PMC478125  PMID: 4277533

Abstract

The incidence of HL-A antigens in patients having a variety of medical conditions, but sharing the common feature of a positive antiglobulin test of the red cells, was determined. There was a significant increase in the antigens HL-A 1 and HL-A 8 and of the 1 and 8 combination when compared with a control group. It is suggested that the presence of these antigens may predispose to autoallergy.

Full text

PDF
353

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Falchuk Z. M., Rogentine G. N., Strober W. Predominance of histocompatibility antigen HL-A8 in patients with gluten-sensitive enteropathy. J Clin Invest. 1972 Jun;51(6):1602–1605. doi: 10.1172/JCI106958. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Fritze D., Herrmann C., Jr, Smith G. S., Walford R. L. HL-A Types in myasthenia gravis. Lancet. 1973 Jul;2(7822):211–passim. doi: 10.1016/s0140-6736(73)93055-9. [DOI] [PubMed] [Google Scholar]
  3. Grumet F. C., Coukell A., Bodmer J. G., Bodmer W. F., McDevitt H. O. Histocompatibility (HL-A) antigens associated with systemic lupus erythematosus. A possible genetic predisposition to disease. N Engl J Med. 1971 Jul 22;285(4):193–196. doi: 10.1056/NEJM197107222850403. [DOI] [PubMed] [Google Scholar]
  4. Katz S. I., Falchuk Z. M., Dahl M. V., Rogentine G. N., Strober W. HL-A8: a genetic link between dermatitis herpetiformis and gluten-sensitive enteropathy. J Clin Invest. 1972 Nov;51(11):2977–2980. doi: 10.1172/JCI107123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Mackay I. R., Morris P. J. Association of autoimmune active chronic hepatitis with HL-A1,8. Lancet. 1972 Oct 14;2(7781):793–795. doi: 10.1016/s0140-6736(72)92149-6. [DOI] [PubMed] [Google Scholar]
  6. Stokes P. L., Asquith P., Holmes G. K., Mackintosh P., Cooke W. T. Histocompatibility antigens associated with adult coeliac disease. Lancet. 1972 Jul 22;2(7769):162–164. doi: 10.1016/s0140-6736(72)91330-x. [DOI] [PubMed] [Google Scholar]
  7. Wenz B., Lalezari P. Methyldopa: physicochemical characterization of the erythrocyte autoantibody. Blood. 1973 Aug;42(2):247–255. [PubMed] [Google Scholar]
  8. White A. C., Barnetson R. S., Costa J. A., McClelland D. B. HL-A and disordered immunity. Lancet. 1973 Jan 13;1(7794):108–108. doi: 10.1016/s0140-6736(73)90513-8. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES