Dear Sir,
We read the current article, “choroidal thickness (CT) changes after dynamic exercise as measured by spectral-domain optical coherence tomography,” with interest.[1] In this well-organized study, authors have investigated CT to be increased when measured 5 min after exercise and normalized at measurement after 15 min. Results are being discussed very well. Besides, we want to make some contributions that may widen discussion area on these findings.
As authors addressed in introduction, choroid is believed to have a role in temperature regulation.[2] Choroid has highest blood flow in the body. Its blood flow is 10 times higher than blood flow through gray matter of brain.[3] However, this high blood flow does not correspond to metabolic requirements. High blood flow of the choroid is believed to protect retina from heat stress.[4] Body temperature rises during exercise. Elevated temperature may harm sensitive retinal cells such as photoreceptors and retina pigment epithelium. Although body temperature is being controlled by hypothalamus during exercise, increase in choroidal blood flow may contribute to this process to protect retina. Retina may need an extra heat lowering mechanism during exercise because of its sensitive structure and heat storing potential of the vitreous. As a result, increase in choroidal blood flow and thereby CT is an expected result. We believe that, finding in this study should also be discussed according to retinal cooling. On the other hand, in a study, CT have found not to be changed by exercise.[5] Average age of patients in this study is 60.6 (±10.4 years) while 27 ± 4.08 in the current study. Age may affect changes in CT.
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References
- 1.Sayin N, Kara N, Pekel G, Altinkaynak H. Choroidal thickness changes after dynamic exercise as measured by spectral-domain optical coherence tomography. Indian J Ophthalmol. 2015;63:445–50. doi: 10.4103/0301-4738.159884. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Nickla DL, Wallman J. The multifunctional choroid. Prog Retin Eye Res. 2010;29:144–68. doi: 10.1016/j.preteyeres.2009.12.002. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3.Alm A, Bill A, Young FA. The effects of pilocarpine and neostigmine on the blood flow through the anterior uvea in monkeys. A study with radioactively labelled microspheres. Exp Eye Res. 1973;15:31–6. doi: 10.1016/0014-4835(73)90186-3. [DOI] [PubMed] [Google Scholar]
- 4.Parver LM, Auker C, Carpenter DO. Choroidal blood flow as a heat dissipating mechanism in the macula. Am J Ophthalmol. 1980;89:641–6. doi: 10.1016/0002-9394(80)90280-9. [DOI] [PubMed] [Google Scholar]
- 5.Alwassia AA, Adhi M, Zhang JY, Regatieri CV, Al-Quthami A, Salem D, et al. Exercise-induced acute changes in systolic blood pressure do not alter choroidal thickness as measured by a portable spectral-domain optical coherence tomography device. Retina. 2013;33:160–5. doi: 10.1097/IAE.0b013e3182618c22. [DOI] [PMC free article] [PubMed] [Google Scholar]