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British Journal of Preventive & Social Medicine logoLink to British Journal of Preventive & Social Medicine
. 1976 Mar;30(1):32–35. doi: 10.1136/jech.30.1.32

Area differences in the incidence of neural tube defect and the rate of spontaneous abortion.

J Fedrick, P Adelstein
PMCID: PMC478935  PMID: 779912

Abstract

In an attempt to corroborate the finding of Roberts and Lloyd (1973) of increased incidence of previous abortions in women living in those areas of South Wales with relatively low incidences of malformations of the central nervous system, we examined the data of the 1958 British Perinatal Mortality Survey. We also found evidence that the history of preceding abortion among all mothers in this survey was slightly more prevalent in areas where the rates of stillbirth and neonatal death from anencephalus or spina bifida were low, but the order of magnitude was much less than in the Welsh study.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alberman E., Creasy M., Polani P. E. Letter: Spontaneous abortion and neural tube defects. Br Med J. 1973 Oct 27;4(5886):230–231. doi: 10.1136/bmj.4.5886.230-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BOOK J. A. The incidence of congenital diseases and defects in a south Swedish population. Acta Genet Stat Med. 1951;2(4):289–311. [PubMed] [Google Scholar]
  3. COFFEY V. P., JESSOP W. J. A study of 137 cases of anencephaly. Br J Prev Soc Med. 1957 Oct;11(4):174–180. doi: 10.1136/jech.11.4.174. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Fedrick J. Anencephalus: variation with maternal age, parity, social class and region in England, Scotland and Wales. Ann Hum Genet. 1970 Jul;34(1):31–38. doi: 10.1111/j.1469-1809.1970.tb00217.x. [DOI] [PubMed] [Google Scholar]
  5. James W. H. Letter: Spontaneous abortion and neural tube defects. Br Med J. 1973 Nov 17;4(5889):425–426. doi: 10.1136/bmj.4.5889.425-d. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Roberts C. J., Lloyd S. Area differences in spontaneous abortion rates in South Wales and their relation to neural tube defect incidence. Br Med J. 1973 Oct 6;4(5883):20–22. doi: 10.1136/bmj.4.5883.20. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. SMILKSTEIN G. A ten-year study of anencephaly. Calif Med. 1962 May;96:350–353. [PMC free article] [PubMed] [Google Scholar]
  8. SMITHELLS R. W., CHINN E. R., FRANKLIN D. ANENCEPHALY IN LIVERPOOL. Dev Med Child Neurol. 1964 Jun;6:231–240. doi: 10.1111/j.1469-8749.1964.tb10782.x. [DOI] [PubMed] [Google Scholar]
  9. SMITHELLS R. W., CHINN E. R. SPINA BIFIDA IN LIVERPOOL. Dev Med Child Neurol. 1965 Jun;7:258–268. [PubMed] [Google Scholar]
  10. STEVENSON A. C., DUDGEON M. Y., McCLURE H. I. Observations on the results of pregnancies in women resident in Belfast. II. Abortions, hydatidiform moles and ectopic pregnancies. Ann Hum Genet. 1959 Dec;23:395–414. doi: 10.1111/j.1469-1809.1959.tb01482.x. [DOI] [PubMed] [Google Scholar]

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