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Box-whisker plots of 24-hour THDOC:THS ratio in the BRIGHT study subgroup (N=232), stratified by (A) rs743572 genotype, (B) rs10786713 genotype and (C) rs2150927 genotype. Plots show the median within the interquartile range box, with whiskers extending to the 5th and 95th percentiles; data points beyond the whiskers are displayed as dots. Groups were compared by Mann-Whitney nonparametric test; *p<0.05, **p<0.01.
