Skip to main content
. 2015 Oct 25;6(41):43363–43374. doi: 10.18632/oncotarget.6222

Figure 1. COX5B is upregulated in breast cancer tissues and cells.

Figure 1

(A) Schematic overview of quantitative stable isotope labelling by amino acids in cell culture (SILAC) and label-free mitochondrial proteomic analysis approaches. (B) The spectrum of COX5B obtained from MS. (C) The fold change of the total proteins from SILAC and the yellow line indicated the relative expression of COX5B (NT VS 16N). (D) The fold change ratio of the breast cancer cells (NT and 16N). (E) Expression of COX5B in two paired normal breast (N), breast cancer (BC) and lymph node (LN) tissues analyzed by Western blot. (F) Immunohistochemistry images of COX5B protein are shown in the large (400 × magnification) and small images (100 × magnification). (G) The mRNA level of COX5B expression in breast cancer cell lines. (H) The protein level of COX5B expression in breast cancer cell lines.